https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Bringing CT Scanners to the Skies: Design of a CT Scanner for an Air Mobile Stroke Unit https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:47959 Wed 13 Mar 2024 07:52:44 AEDT ]]> Does variability in automated perfusion software outputs for acute ischemic stroke matter? Reanalysis of EXTEND perfusion imaging https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46485 70 ml (n = 9), and no perfusion lesion/lack of penumbral tissue (n = 20). The revised perfusion lesion volumes were significantly smaller compared to the original RAPID volumes (median 68 ml IQR 34–102 ml vs. 42 ml 16–92 ml, p = 0.036). Of the patients who met the revised mismatch criteria, 40% receiving alteplase had modified Rankin Scale (mRS) 0–1 at 3-month compared to 28% with placebo (Adjusted Odds Ratio (OR) = 2.23, CI 1.08–4.58, p = 0.028). In contrast, in the original mismatch cohort, 35% receiving alteplase had mRS 0–1 at 3-month compared to 30% with placebo (adjusted OR = 1.88, p = 0.056). Conclusions: These data reinforce the benefit of alteplase in the later time window, and suggest that differences in automated perfusion imaging software outputs may be clinically relevant.]]> Wed 13 Mar 2024 07:51:52 AEDT ]]> A randomized trial of tenecteplase versus alteplase for acute ischemic stroke https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:13689 Wed 11 Apr 2018 12:02:09 AEST ]]> Stroke doctors: who are we? A World Stroke Organization survey https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34647 1 million population and other countries with > 50 million population were included (n = 49, total 5.6 billion inhabitants, 85% of global strokes). Two stroke experts from each selected country were surveyed, discrepancies resolved, and further information on identified stroke-specific curricula sought. Results: We received responses from 48 (98%) countries. Of ischemic stroke patients, 64% were reportedly treated by neurologists, ranging from 5% in Ireland to 95% in the Netherlands. Per thousand annual strokes there were average six neurologists, ranging from 0.3 in Ethiopia to 33 in Israel. Of intracerebral hemorrhage patients, 29% were reportedly treated by neurosurgeons, ranging from 5% in Sweden to 79% in Japan, with three neurosurgeons per thousand strokes, ranging from 0.1 in Ethiopia to 24 in South Korea. Most countries had a stroke society (86%) while only 10 (21%) had a degree or subspecialty for stroke medicine. Conclusions: Stroke doctor numbers, background specialties, and opportunities to specialize in stroke vary across the globe. Most countries have a scientific society to pursue advancement of stroke medicine, but few have stroke curricula.]]> Wed 09 Mar 2022 15:59:08 AEDT ]]> Tenecteplase versus alteplase in stroke thrombolysis: an individual patient data meta-analysis of randomized controlled trials https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:25490 Thu 17 Mar 2022 14:34:05 AEDT ]]> Artificial neural network computer tomography perfusion prediction of ischemic core https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36875 Thu 04 Nov 2021 10:38:49 AEDT ]]> Multiattribute selection of acute stroke imaging software platform for Extending the Time for Thrombolysis in Emergency Neurological Deficits (EXTEND) clinical trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:19971 Sat 24 Mar 2018 07:54:29 AEDT ]]> Multi-modal CT in acute stroke: wait for a serum creatinine before giving intravenous contrast? No! https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26876 Sat 24 Mar 2018 07:41:43 AEDT ]]> Perfusion/diffusion mismatch is valid and should be used for selecting delayed interventions https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:23766 Sat 24 Mar 2018 07:11:08 AEDT ]]>